Annual report pursuant to Section 13 and 15(d)

Shareholders' Equity (Details 2)

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Shareholders' Equity (Details 2) - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Total research and development expenses $ 5,853,291 $ 3,965,543
Total general and administrative expenses 5,074,694 4,279,357
Total stock-based compensation expense 2,014,246 1,602,318
Stock Options [Member]    
Research and development options expense 252,173 355,229
Total research and development expenses 252,173 355,229
General and administrative options expense 1,168,281 723,344
Stock and warrants issued to consultants and employees 710,792 523,745
Total general and administrative expenses 1,879,073 1,247,089
Total stock-based compensation expense $ 2,131,246 $ 1,602,318